Results for 'Fast Alf Michael'

977 found
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  1.  9
    Vorträge und kleinere Arbeiten. 1934–1935Vorträge und kleinere Arbeiten. 1934–1935, Karl Barth-Gesamtausgabe, Band 52, hg. von Michael Beintker, Michael Hüttenhoff und Peter Zocher. [REVIEW]Alf Christophersen - 2019 - Journal for the History of Modern Theology/Zeitschrift für Neuere Theologiegeschichte 26 (2):130-136.
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  2.  4
    God and his demons.Michael Parenti - 2010 - Amherst, N.Y.: Prometheus Books.
    Part I: All in the Bible -- Up from heaven -- The great exterminator -- The great abominator -- The other face of our sweet Savior -- Who killed Jesus and all those other Jews? -- Part II: Divine design -- Working his blunders in mysterious ways -- Jiffy creation, dubious design -- Part III: When the ethereal becomes material -- Mother Teresa, John Paul, and the fast-track saints -- Cashing in on heaven -- Moneyed gurus and cults -- (...)
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  3.  5
    Karl Barth, Vorträge und kleinere Arbeiten. 1934–1935, Karl Barth-Gesamtausgabe, Band 52, hg. von Michael Beintker, Michael Hüttenhoff und Peter ZocherVorträge und kleinere Arbeiten. 1934–1935, Karl Barth-Gesamtausgabe, Band 52, hg. von Michael Beintker, Michael Hüttenhoff und Peter Zocher. [REVIEW]Alf Christophersen - 2019 - Journal for the History of Modern Theology/Zeitschrift für Neuere Theologiegeschichte 26 (2):130-136.
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  4.  3
    The kitchen chronicles: 1001 lunches with J. Krishnamurti.Michael Krohnen - 1997 - Ojai, Calif.: Edwin House.
    The Kitchen Chronicles is a moving and surprisingly humorous memoir by the cook to one of the th Centurys great figures, Indian-born philosopher J. Krishnamurti. In a modern quest for truth the author chronicles the daily life in Krishnamurtis kitchen and at his table. This insightful, fast-paced memoir reveals the private life of Krishnamurti, his splendid sense of humor, his affectionate friendships, and probing intelligence. Photographs place Krishnamurti in his California home with friends and associates.
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  5. Fast and Frugal Heuristics.Michael A. Bishop - 2006 - Philosophy Compass 1 (2):201–223.
    A heuristic is a rule of thumb. In psychology, heuristics are relatively simple rules for making judgments. A fast heuristic is easy to use and allows one to make judgments quickly. A frugal heuristic relies on a small fraction of the available evidence in making judgments. Typically, fast and frugal heuristics (FFHs) have, or are claimed to have, a further property: They are very reliable, yielding judgments that are about as accurate in the long run as ideal non- (...), non-frugal rules. This paper introduces some well-known examples of FFHs, raises some objections to the FFH program, and looks at the implications of those parts of the FFH program about which we can have some reasonable degree of confidence. (shrink)
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  6.  14
    Psychological plausibility of the theory of probabilistic mental models and the fast and frugal heuristics.Michael R. Dougherty, Ana M. Franco-Watkins & Rick Thomas - 2008 - Psychological Review 115 (1):199-211.
  7.  15
    Non-static framework for understanding adaptive designs: an ethical justification in paediatric trials.Michael O. S. Afolabi & Lauren E. Kelly - 2021 - Journal of Medical Ethics 48 (11):825-831.
    Many drugs used in paediatric medicine are off-label. There is a rising call for the use of adaptive clinical trial designs in responding to the need for safe and effective drugs given their potential to offer efficiency and cost-effective benefits compared with traditional clinical trials. ADs have a strong appeal in paediatric clinical trials given the small number of available participants, limited understanding of age-related variability and the desire to limit exposure to futile or unsafe interventions. Although the ethical value (...)
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  8. The university in the epoch of digital reason : fast knowledge in the circuits of cybernetic capitalism.Michael A. Peters - 2015 - In Paul Gibbs (ed.), Universities in the flux of time: an exploration of time and temporality in university life. New York: Routledge.
     
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  9.  38
    How fast does a child learn a word?Michael Maratsos - 2001 - Behavioral and Brain Sciences 24 (6):1111-1112.
    This discussion argues that for many word meanings, the child has to assemble a new category, using relatively slow information-sifting processes. This does not cause high semantic errors, because children probably hold off using a word until much such sifting has occurred, rather than producing the new word as soon as they have any information on it.
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  10. Code is Law: Subversion and Collective Knowledge in the Ethos of Video Game Speedrunning.Michael Hemmingsen - 2020 - Sport, Ethics and Philosophy 15 (3):435-460.
    Speedrunning is a kind of ‘metagame’ involving video games. Though it does not yet have the kind of profile of multiplayer e-sports, speedrunning is fast approaching e-sports in popularity. Aside from audience numbers, however, from the perspective of the philosophy of sport and games, speedrunning is particularly interesting. To the casual player or viewer, speedrunning appears to be a highly irreverent, even pointless, way of playing games, particularly due to the incorporation of “glitches”. For many outside the speedrunning community, (...)
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  11.  17
    Churches claiming a right to the city? Lived urbanisms in the City of Tshwane.Michael Ribbens & Stephan F. De Beer - 2017 - HTS Theological Studies 73 (3).
    This article sets out to describe how churches have responded and continue to respond to fast-changing urban environments in Pretoria Central and Mamelodi East, animating Henri Lefebvre’s sociological perspective of citadins or urban inhabitants. We make tentative interpretations and offer critical appreciation. Churches, which were historically separated from the city centre, now directly participate in claiming a right to the city. With necessary fluidity, churches express lived African urbanisms through informality, place-making, spatial innovation and everyday rituals. Though not exhaustive, (...)
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  12. Medical Futility and Physician Discretion.Michael Wreen - 2007 - The Proceedings of the Twenty-First World Congress of Philosophy 1 (3):257-267.
    Some patients have no chance of surviving if not treated, but very little chance if treated. A number of medical ethicists and physicians have argued that treatment in such cases is medically futile and a matter of physician discretion. This paper is a critical examination of that position. According to Howard Brody and others, a judgment of medical futility is a purely technical matter, and one which physicians are uniquely qualified to make. Although Brody later retracted these claims, he held (...)
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  13.  9
    Gauss and the history of the fast Fourier transform.Michael T. Heideman, Don H. Johnson & C. Sidney Burrus - 1985 - Archive for History of Exact Sciences 34 (3):265-277.
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  14.  6
    Movement and Time in the Cyberworld: Questioning the Digital Cast of Being.Michael Eldred - 2019 - De Gruyter.
    The cyberworld fast rolling in and impacting every aspect of human living on the globe today presents an enormous challenge to humankind. It is taken up by the media following current events through to all kinds of natural- and social-scientific discourses. Digitized technoscience develops at a breakneck pace in all areas accompanied by sociological analysis. What is missing is a philosophical response genuinely posing the basic ontological question: What is a digital being's peculiar mode of being? The present study (...)
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  15.  53
    Stimulating Reflection and Self-correcting Reasoning Through Argument Mapping: Three Approaches.Michael H. G. Hoffmann - 2018 - Topoi 37 (1):185-199.
    A large body of research in cognitive science differentiates human reasoning into two types: fast, intuitive, and emotional “System 1” thinking, and slower, more reflective “System 2” reasoning. According to this research, human reasoning is by default fast and intuitive, but that means that it is prone to error and biases that cloud our judgments and decision making. To improve the quality of reasoning, critical thinking education should develop strategies to slow it down and to become more reflective. (...)
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  16.  5
    Religion und die umstrittene Moderne.Michael Reder & Matthias Rugel (eds.) - 2010 - Kohlhammer Verlag.
    Religionen sind auf vielfaltige, oft widerspruchliche Weise in offentliche Diskurse und politische Prozesse zuruckgekehrt. Sie spielen heute fast in allen Regionen und auch auf globaler Ebene eine wichtige Rolle. Andererseits sind religiose Fundamentalismen oder die politische Instrumentalisierung von Religionen in Konflikten bedrohliche Phanomene, die sich weltweit ausbreiten. So ambivalent wie die Religionen ist auch die Moderne. Die klassische, westliche Moderne mit ihrer Orientierung an selbstverantwortlicher Gestaltung der Welt, Demokratie und Menschenrechten ist fragwurdig geworden: Desorientierung und globale soziale, okonomische wie (...)
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  17.  14
    “Boiling up the problem of violence” in childbirth?—an ethical viewpoint on medical professional responses to women’s reports of mistreatment in childbirth.Michael Rost, Louisa Arnold & Eva De Clercq - 2020 - Ethik in der Medizin 32 (2):189-193.
    In den letzten Jahren berichteten mehr und mehr Frauen von Gewalt und Respektlosigkeit in der Geburtshilfe. Inzwischen hat sich auch die Forschung verstärkt dieses Themas angenommen. Prävalenzschätzungen sind jedoch aufgrund erheblicher methodischer Schwächen noch nicht hinreichend genau zu beziffern. Die Vielzahl und Vielfalt der bestehenden Forschungsergebnisse lassen dennoch den Schluss zu, dass es in der Geburtshilfe in fast allen Regionen der Erde regelmäßig zu Gewalt und Respektlosigkeit und damit zu Menschenrechtsverletzungen kommt. Die Folgen reichen bis hin zu Posttraumatischen Belastungsstörungen, (...)
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  18.  9
    Technical Careers for Women: a Perspective From Rural Appalachia.Michael N. Bishara - 1987 - Bulletin of Science, Technology and Society 7 (1-2):260-272.
    The onset of the electronics-based information revolution will augur changes in the sociological perceptions of 'suitable careers' for women. This phenomenon is particularly evident in rural Appalachia. A planned, systematic delivery system was designed, developed, and implemented by Southwest Virginia Community College to introduce women to the challenges and possibilities of technical careers. This was accomplished through a gradualized phase-in to Technological Literacy, followed by in-depth involvement, culminating in an industrial internship experience. A special curriculum was designed to ease the (...)
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  19.  8
    Remembering Herb Fingarette.Michael Nylan - 2022 - Philosophy East and West 72 (4):857–860.
    In lieu of an abstract, here is a brief excerpt of the content:Remembering Herb FingaretteMichael Nylan (bio)Over the years, several people have remarked to me that Herb "disappeared" or "disengaged" after his retirement. His standing, at the time of his retirement, was beautifully captured in the 1999 volume Rules, Rituals, and Responsibility: Essays Dedicated to Herbert Fingarette, edited by his student Mary Bockover.But remembering Herb Fingarette, I recall the first two times I spoke with him, by email and eventually in (...)
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  20.  18
    The Dialectical Relationship Between Place and Space in Education: How the Internet Is Changing Our Perceptions of Teaching and Learning.Michael Glassman & Jonathan Burbidge - 2014 - Educational Theory 64 (1):15-32.
    In this essay Michael Glassman and Jonathan Burbidge explore the idea of a dialectical relationship between the traditional place(s) of teaching/learning settings and the challenges to our perceptions created by the new spaces of the Internet. The authors examine this topic in the context of a three-stage evolution of humans' relationship with new technologies: (1) fear of how new technologies will change our everyday actions, (2) recognition of emerging technologies as tools capable of offering new possibilities in our activities, (...)
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  21.  8
    American Exceptionalism and Human Rights.Michael Ignatieff (ed.) - 2005 - Princeton University Press.
    With the 2003 invasion and subsequent occupation of Iraq, the most controversial question in world politics fast became whether the United States stands within the order of international law or outside it. Does America still play by the rules it helped create? American Exceptionalism and Human Rights addresses this question as it applies to U.S. behavior in relation to international human rights. With essays by eleven leading experts in such fields as international relations and international law, it seeks to (...)
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  22.  15
    Is science reporting turning into fast food?Michael Gross - 2009 - Ethics in Science and Environmental Politics 9 (1):5-7.
  23.  6
    Chapter Sixteen.Michael Boylan - 2007 - In The Extinction of Desire. Oxford, UK: Blackwell. pp. 175–187.
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  24.  19
    Hans Jonas-Handbuch: Leben – Werk – Wirkung.Michael Bongardt, Holger Burckhart, John-Stewart Gordon & Jürgen Nielsen-Sikora (eds.) - 2021 - J.B. Metzler.
    Hans Jonas ist einer der bedeutenden Denker des 20. Jahrhunderts. Das Handbuch erklärt die philosophischen, theologischen und naturwissenschaftlichen Kontexte, die sein Denken geprägt haben. Es präsentiert neben Informationen zur Biographie und den zeitgenössischen Bezügen alle wichtigen Werke und gibt Hinweise zu deren internationaler Rezeption in vielen Disziplinen. Zentrale Begriffe und Konzepte im Gesamtwerk von Hans Jonas werden ausführlich erklärt. Das internationale Autorenteam der über 50 Expertinnen und Experten aus fast 20 Ländern zeigt nicht nur das bis heute weltweite Interesse (...)
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  25.  40
    Striking a Balance: A Primer in Traditional Asian Values.Michael C. Brannigan - 2009 - Lexington Books.
    Introduction -- Hindu ethics -- Life's four goals -- Paths to Enlightenment -- Karma and rebirth -- Shades of Dharma -- Buddhist ethics -- The middle path -- The four noble truths -- In the wake of karma -- The four supreme virtues -- What is a Buddhist social ethics? -- Zen Buddhist ethics -- A way of the monk : practice is attainment -- A way of the warrior -- A way of tea : the virtue of presence -- (...)
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  26.  8
    Matter and meaning: is matter sacred or profane?Michael Fuller (ed.) - 2010 - Newcastle upon Tyne: Cambridge Scholars Press.
    We live in a material world. But what is matter? Can it point us towards meanings outside itself, or can any meaning it possesses only be invested in it by human beings? To what extent might these semantic activities overlap? How have our current understandings of matter and meaning developed from those of past thinkers, in both Western and non-Western contexts? These and many other questions were addressed at a conference held under the auspices of the Science and Religion Forum (...)
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  27.  57
    Models in fluid dynamics.Michael Heidelberger - unknown
    In this paper, I would like to show that considering technological models as they arise in engineering disciplines can greatly enrich the philosophical perspective on models. In fluid mechanics, (at least) three types of models are distinguished: mathematical, computer and physical models. Very often, the choice of a particular mathematical, computer or physical model highly affects the type of solutions and the computational time needed for it. Technological models not only aim at a correct description of the physical phenomena, but (...)
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  28.  4
    Für die Ausschöpfung der sportsoziologischen Potenziale der Akteur-Netzwerk-Theorie.Michael Staack - 2022 - Sport Und Gesellschaft 19 (3):335-364.
    Zusammenfassung Die Akteur-Netzwerk-Theorie findet in insbesondere der deutschen Sportsoziologie fast keine Verwendung. Der Artikel plädiert für die Ausschöpfung ihrer sportsoziologischen Potenziale. Er argumentiert, dass das Potenzial der ANT insbesondere darin besteht, dass sie eine spezifische Sensibilität für die Instabilität bzw. für die Unwahrscheinlichkeit sozialer Ordnungsbildung aufweist: Indem sie erstens die Materialität des Sozialen und zweitens die beständige Dynamik des (materiellen) Sozialen berücksichtigen kann, kann die ANT nicht nur materiell basierte Ordnungsbildung, sondern in besonderer Weise auch die Unwahrscheinlichkeit (auch) materiell (...)
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  29.  32
    Simplicity and Robustness of Fast and Frugal Heuristics.Martignon Laura & Schmitt Michael - 1999 - Minds and Machines 9 (4):565-593.
    Intractability and optimality are two sides of one coin: Optimal models are often intractable, that is, they tend to be excessively complex, or NP-hard. We explain the meaning of NP-hardness in detail and discuss how modem computer science circumvents intractability by introducing heuristics and shortcuts to optimality, often replacing optimality by means of sufficient sub-optimality. Since the principles of decision theory dictate balancing the cost of computation against gain in accuracy, statistical inference is currently being reshaped by a vigorous new (...)
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  30.  6
    Fast and optimal decoding for machine translation.Ulrich Germann, Michael Jahr, Kevin Knight, Daniel Marcu & Kenji Yamada - 2004 - Artificial Intelligence 154 (1-2):127-143.
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  31.  13
    The aporetic humanism of early Derrida.Michael Williams - 2023 - Philosophy and Social Criticism 49 (7):814-838.
    This article focuses on the French philosopher Jacques Derrida’s thought in the 1960s. Though the discourse of the ‘death of man’ was regnant among French avant-garde intellectuals, this article argues that Derrida himself has to be described as a humanist at this stage in his career, even if a reluctant one. The case is made through close textual analysis of three of Derrida’s early and seminal works: ‘Cogito and the History of Madness’ (1963), ‘Violence and Metaphysics: An Essay on the (...)
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  32.  8
    Einleitung: Polyamorie.Kühler Michael & Janina Loh - 2023 - Zeitschrift für Praktische Philosophie 10 (2).
    Die Vorstellung, dass wir mehrere Menschen zugleich lieben können, wird in modernen, westlich geprägten Gesellschaften sowohl als fast trivialerweise wahr anerkannt, als auch als grundsätzlich verfehlt abgelehnt. Während beispielsweise kein Zweifel daran besteht, dass wir üblicherweise unsere Eltern und zeitgleich etwaige Geschwister sowie umgekehrt Eltern für gewöhnlich alle ihre Kinder lieben und wir zudem zumeist mehrere enge und tiefe Freundschaften pflegen, ist die gesellschaftlich vorherrschende Auffassung von romantischer Liebe weitgehend von der Idee geprägt, dass es sich ausschließlich um exklusive (...)
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  33. Can evolution get us off the hook? Evaluating the ecological defence of human rationality.Maarten Boudry, Michael Vlerick & Ryan McKay - 2015 - Consciousness and Cognition 33:524-535.
    This paper discusses the ecological case for epistemic innocence: does biased cognition have evolutionary benefits, and if so, does that exculpate human reasoners from irrationality? Proponents of ‘ecological rationality’ have challenged the bleak view of human reasoning emerging from research on biases and fallacies. If we approach the human mind as an adaptive toolbox, tailored to the structure of the environment, many alleged biases and fallacies turn out to be artefacts of narrow norms and artificial set-ups. However, we argue that (...)
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  34.  76
    Ethical Criteria for Human Challenge Studies in Infectious Diseases: Table 1.Ben Bambery, Michael Selgelid, Charles Weijer, Julian Savulescu & Andrew J. Pollard - 2016 - Public Health Ethics 9 (1):92-103.
    Purposeful infection of healthy volunteers with a microbial pathogen seems at odds with acceptable ethical standards, but is an important contemporary research avenue used to study infectious diseases and their treatments. Generally termed ‘controlled human infection studies’, this research is particularly useful for fast tracking the development of candidate vaccines and may provide unique insight into disease pathogenesis otherwise unavailable. However, scarce bioethical literature is currently available to assist researchers and research ethics committees in negotiating the distinct issues raised (...)
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  35.  12
    So Much, so Fast, so Little Time: Coming to Terms with Rapid Change and its Consequences: Coming to Terms with Rapid Change and its Consequences.Michael St Clair - 2011 - Praeger.
    Introduction and acknowledgments -- What is happening to us? and why? -- So much information is changing how we think -- Communication, entertainment, and over-stimulation -- Work : how it changes and how it changes us -- New behaviors and changes in manners -- Faster and faster time -- Families, women, and sex -- Making sense of contradictory social trends -- Conclusion.
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  36.  18
    Shut-Up and Listen: Implications and Possibilities of Albert Memmi’s Characteristics of Colonization Upon the “Natural World”.Michael De Danann Sitka-Sage, Laura Piersol, Ramsey Affifi & Sean Blenkinsop - 2016 - Studies in Philosophy and Education 36 (3):349-365.
    This paper begins by exploring the anti-colonial work of Tunisian scholar Albert Memmi in his classic book The Colonizer and the Colonized and determining whether the characteristics of colonization that he names can be successfully applied to the current relationship between modern humans and the “natural world”. After considering what we found to be the five key characteristics: manufacturing the colonial, alienation and unknowability, violence, psychological strategies, and language, history, and metaphor we draw clear parallels, through selected examples, to the (...)
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  37.  20
    Shut-Up and Listen: Implications and Possibilities of Albert Memmi’s Characteristics of Colonization Upon the “Natural World”.Michael Danann Sitka-Sage, Laura Piersol, Ramsey Affifi & Sean Blenkinsop - 2017 - Studies in Philosophy and Education 36 (3):349-365.
    This paper begins by exploring the anti-colonial work of Tunisian scholar Albert Memmi in his classic book The Colonizer and the Colonized and determining whether the characteristics of colonization that he names can be successfully applied to the current relationship between modern humans and the “natural world”. After considering what we found to be the five key characteristics: manufacturing the colonial, alienation and unknowability, violence, psychological strategies, and language, history, and metaphor we draw clear parallels, through selected examples, to the (...)
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  38.  22
    Ethics in business and administration: An international and historical perspective. [REVIEW]Michael W. Small - 1993 - Journal of Business Ethics 12 (4):293 - 300.
    This is a study of ethical and moral behavior, or perhaps unethical behavior, in two different societies. One society, contemporary Australia and in particular the state of Western Australia, is currently undergoing an exhaustive Royal Commission into the shenanigans of a number of well-known business men and former leading politicians who seem to have been playing fast and loose with large amounts of other peoples' money. While this was initially the major focus of the paper, a secondary focus developed (...)
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  39. That busyness that is not business: Nervousness and character at the turn of the last century.Michael O'Malley - 2005 - Social Research: An International Quarterly 72 (2):371-406.
    From 1897 through about 1912, film producers would shoot their footage and then make a contact print of the entire film on a roll of photographic paper. Mailed to the Library of Congress, these rolls of paper established copyright. The films document a very busy world indeed. They show people thronging streets, working, shopping; they show crowds shuffling through gates at Ellis Island or welcoming returning war heroes. More than just documentary, the films include satire ad commentary on the nature (...)
     
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  40.  20
    AddingSpace to Your Class Discussions.Kelly C. Smith, Michael Doyle, Anna Dueholm, Aundrea Gibbons, Austin Macdonald-Shedd, Isabela Parise, Jake Ballard, Stephen Galaida, Nathan Stolzenfeld & Joseph Walker - 2022 - Teaching Ethics 22 (2):269-290.
    Our capabilities in space are growing almost as fast as our ambitions. Many nations, companies, and private actors are currently vying to secure historic “firsts” in space, raising complex social and ethical questions. There is surprisingly little serious analysis of these issues, however, and they are rarely discussed in undergraduate class discussions, despite their popularity with students. To help correct this deficit, a student research team designed 11 case studies to help instructors across the curriculum introduce space into their (...)
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  41.  17
    A view from mindreading on fast-and-slow thinking.Jason Low, Stephen A. Butterfill & John Michael - 2023 - Behavioral and Brain Sciences 46:e130.
    De Neys's incisive critique of empirical and theoretical research on the exclusivity feature underscores the depth of the challenge of explaining the interplay of fast and slow processes. We argue that a closer look at research on mindreading reveals abundant evidence for the exclusivity feature – as well as methodological and theoretical perspectives that could inform research on fast and slow thinking.
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  42.  31
    Shut-Up and Listen: Implications and Possibilities of Albert Memmi’s Characteristics of Colonization Upon the “Natural World”.Sean Blenkinsop, Ramsey Affifi, Laura Piersol & Michael De Danann Sitka-Spruce - 2017 - Studies in Philosophy and Education 36 (3):349-365.
    This paper begins by exploring the anti-colonial work of Tunisian scholar Albert Memmi in his classic book The Colonizer and the Colonized and determining whether the characteristics of colonization that he names can be successfully applied to the current relationship between modern humans and the “natural world”. After considering what we found to be the five key characteristics: manufacturing the colonial, alienation and unknowability, violence, psychological strategies (bad faith), and language, history, and metaphor we draw clear parallels, through selected examples, (...)
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  43.  11
    The Oxford Handbook of Music Psychology.Susan Hallam, Ian Cross & Michael Thaut (eds.) - 2009 - Oxford University Press UK.
    The 2nd edition of the Oxford Handbook of Music Psychology updates the original landmark text which provided a comprehensive review of the latest developments in this fast growing area of research. The 2nd edition has 55 chapters divided into 11 parts covering both experimental and theoretical perspectives each edited by an internationally recognised authority in the area.
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  44. Der „kontrollierte individuelle Heilversuch“ als neues Instrument bei der klinischen Erstanwendung risikoreicher Therapieformen – Ethische Analyse einer somatischen Gentherapie für das Wiskott-Aldrich-Syndrom.Thomas Heinemann, Bert Heinrichs, Christoph Klein, Michael Fuchs & Dietmar Hübner - 2006 - Jahrbuch für Wissenschaft Und Ethik 11 (1):153-199.
    Das Wiskott-Aldrich-Syndrom (WAS), ein genetisch bedingter Immundefekt mit klinischer Manifestation im Kleinkindalter, wird voraussichtlich in näherer Zukunft erstmals versuchsweise durch eine somatische Gentherapie behandelt werden. Im vor- liegenden Beitrag werden die wichtigsten medizinisch-naturwissenschaftlichen Fakten dieses Krankheitsbildes sowie die bisherigen Erfahrungen mit somatischen Gentherapien bei anderen Immunmangelsyndromen ausführlich dargestellt. Sodann erfolgt eine ethische Analyse eines möglichen gentherapeutischen Eingriffs bei WAS-Patienten, bei der die spezifischen Aspekte des Wiskott-Aldrich-Syndroms – insbesondere die fast ausschließliche Betroffenheit von Kindern sowie die unterschiedlich aussichtsreiche Alter- nativoption (...)
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  45.  68
    Perspectives on computing ethics: a multi-stakeholder analysis.Damian Gordon, Ioannis Stavrakakis, J. Paul Gibson, Brendan Tierney, Anna Becevel, Andrea Curley, Michael Collins, William O’Mahony & Dympna O’Sullivan - 2022 - Journal of Information, Communication and Ethics in Society 20 (1):72-90.
    Purpose Computing ethics represents a long established, yet rapidly evolving, discipline that grows in complexity and scope on a near-daily basis. Therefore, to help understand some of that scope it is essential to incorporate a range of perspectives, from a range of stakeholders, on current and emerging ethical challenges associated with computer technology. This study aims to achieve this by using, a three-pronged, stakeholder analysis of Computer Science academics, ICT industry professionals, and citizen groups was undertaken to explore what they (...)
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  46.  24
    Atlas stumbled: Kinesin light chain‐1 variant E triggers a vicious cycle of axonal transport disruption and amyloid‐β generation in Alzheimer's disease.Kathlyn J. Gan, Takashi Morihara & Michael A. Silverman - 2015 - Bioessays 37 (2):131-141.
    Substantial evidence implicates fast axonal transport (FAT) defects in neurodegeneration. In Alzheimer's disease (AD), it is controversial whether transport defects cause or arise from amyloid‐β (Aβ)‐induced toxicity. Using a novel, unbiased genetic screen, Morihara et al. identified kinesin light chain‐1 splice variant E (KLC1vE) as a modifier of Aβ accumulation. Here, we propose three mechanisms to explain this causal role. First, KLC1vE reduces APP transport, leading to Aβ accumulation. Second, reduced transport of APP by KLC1vE triggers an ER stress (...)
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  47.  16
    Directives and norms.Alf Ross - 1968 - Clark, NJ: Lawbook Exchange. Edited by Brian Loar.
    Ross, Alf Loar, Brian, Editor.Directives and Norms. New York: Humanities Press, [1967]. ix, 188 pp. Reprint available April 2009 by The Lawbook Exchange, Ltd. ISBN-13: 978-1-58477-961-2. ISBN-10: 1-58477-961-6. Cloth with dust jacket. $65.00 * Reprint of the first American edition. One of the most interesting jurists of the post-World War II era, Ross [1899-1979] was a legal and moral philosopher, scholar of international law and the leading representative of Scandinavian Legal Realism. This book and On Law and Justice (1958) are (...)
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  48.  9
    Directives and norms.Alf Ross - 1968 - Clark, NJ: Lawbook Exchange. Edited by Brian Loar.
    Reprint of the first American edition. One of the most interesting jurists of the post-World War II era, Ross [1899-1979] was a legal and moral philosopher, scholar of international law and the leading representative of Scandinavian Legal Realism. This book and On Law and Justice (1958) are his principal works. In Directives and Norms Ross asks whether imperatives (or, to use his term, 'directives') are subject to logic in the same way as indicatives. He shows the difference between indicative and (...)
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  49. In defence of ontological emergence and mental causation.Michael Silberstein - 2006 - In Philip Clayton & Paul Davies (eds.), The re-emergence of emergence: the emergentist hypothesis from science to religion. New York: Oxford University Press. pp. 203.
  50. Attention, seeing, and change blindness.Michael Tye - 2010 - Philosophical Issues 20 (1):410-437.
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